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Stock comparison · Signal date 2026-11-06

BMRN vs SYRE: stock comparison and AI forecast

Biomarin Pharmaceutical Inc (BMRN) and Spyre Therapeutics, Inc. (SYRE) compared on price performance, valuation, profitability and the daily AI forecast. · Alpha · vs market

Share
Nasdaq · Pharmaceutical Preparations

BMRN Biomarin Pharmaceutical Inc

Market Cap
$10.85B
P/E Ratio
560.3x
Size
large-cap
AI Forecast
Full analysis →
Nasdaq · Pharmaceutical Preparations

SYRE Spyre Therapeutics, Inc.

Price
$103.86 +42.1% · 6M
Market Cap
$9.16B
P/E Ratio
–
Size
mid-cap
AI Forecast
Full analysis →
Model output

Which one does the AI model favor?

Intratio's model scores both stocks every trading day. Sign in to see their current direction; the exact ratings and forecasts come with a plan or a free follow slot.

BMRN · SYRE

Key facts

  • BMRN is 1.2 times larger than SYRE by market capitalization ($10.85B against $9.16B).
  • BMRN carries 0.85 times debt per unit of equity, against 0.05 times for SYRE.
  • Both companies share the SEC industry classification Pharmaceutical Preparations.
Fundamentals

Fundamentals side by side

Trailing twelve months.

Valuation & Market

MetricBMRNSYRE
Market Cap$10.85B$9.16B
P/E Ratio560.31x–
P/B Ratio1.73x8.71x
EPS$0.10$-2.19
Book Value/Share$32.32$11.93
Revenue/Share$18.88–
FCF/Share$2.88–

Profitability & Margins

MetricBMRNSYRE
ROE–-25.1%
ROA–-24.0%
ROIC1.1%-23.6%
Gross Margin76.0%–
Operating Margin3.1%–
EBT Margin1.2%–
Tax Rate143.8%0.0%

Financial Health

MetricBMRNSYRE
Current Ratio2.44x27.40x
Quick Ratio1.32x–
D/E Ratio0.85x0.05x
Financial Leverage1.85x1.05x
Working Capital$2.32B$1.06B

Cash Flow

MetricBMRNSYRE
Operating Cash Flow$677M-$249M
Free Cash Flow$558M–
Capital Spending-$119M–
OCF Growth YoY-26.0%–
FCF Growth YoY-33.0%–
FCF/Sales15.3%–
CapEx/Sales3.2%–

Operational Efficiency

MetricBMRNSYRE
Asset Turnover0.32x–
Receivables Turnover3.4x–
Inventory Turnover0.5x–
Fixed Assets Turnover3.7x–
Days Sales Outstanding107 days–
Days Inventory746 days–
Payables Period54 days–
Cash Conversion Cycle799 days–

Income Statement

MetricBMRNSYRE
Total Revenue$3.66B–
Operating Income$114M-$250M
Net Income–-$264M
R&D Expense$759M$260M
SG&A Expense$1.43B–
Cost of Goods Sold$879M–

Dividend & Shareholder Information

MetricBMRNSYRE
Shares Outstanding194M88M
EPS Growth-95.4%–
FAQ

BMRN vs SYRE: stock comparison and AI forecast

Which is bigger, BMRN or SYRE?

BMRN is 1.2 times larger than SYRE by market capitalization ($10.85B against $9.16B).

Which one does Intratio's AI model rank higher, BMRN or SYRE?

Intratio's model scores both stocks every trading day. Sign in to see their current direction; the exact ratings and forecasts come with a plan or a free follow slot.

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This analysis is generated automatically using our proprietary AI systems and should not be considered personalized investment advice. Past performance does not guarantee future results. Always conduct your own research and consider consulting a financial advisor before making investment decisions.