Intratio
Loading...
Skip to main content
Stock comparison · Signal date 2026-11-06

ARWR vs PTGX: stock comparison and AI forecast

Arrowhead Pharmaceuticals, Inc. (ARWR) and Protagonist Therapeutics, Inc (PTGX) compared on price performance, valuation, profitability and the daily AI forecast. · Alpha · vs market

Share
Nasdaq · Pharmaceutical Preparations

ARWR Arrowhead Pharmaceuticals, Inc.

Price
$58.16 -25.4% · 6M
Market Cap
$8.22B
P/E Ratio
–
Size
mid-cap
AI Forecast
Full analysis →
Nasdaq · Pharmaceutical Preparations

PTGX Protagonist Therapeutics, Inc

Price
$132.04 +33.6% · 6M
Market Cap
$8.54B
P/E Ratio
33.6x
Size
mid-cap
AI Forecast
Full analysis →
Model output

Which one does the AI model favor?

Intratio's model scores both stocks every trading day. Sign in to see their current direction; the exact ratings and forecasts come with a plan or a free follow slot.

6M · 2026-05-07 → 2026-11-06

Six-month price performance

Closing prices rebased to 100 at the start of the window.

80100120140160
ARWR -25.4% PTGX +33.6%
ARWR · PTGX

Key facts

  • ARWR and PTGX have similar market capitalizations ($8.22B and $8.54B).
  • Over the last six months PTGX returned +33.6% and ARWR -25.4%.
  • ARWR carries 3.54 times debt per unit of equity, against 0.06 times for PTGX.
  • Both companies share the SEC industry classification Pharmaceutical Preparations.
Fundamentals

Fundamentals side by side

Trailing twelve months.

Valuation & Market

MetricARWRPTGX
Market Cap$8.22B$8.54B
P/E Ratio–33.60x
P/B Ratio17.65x7.88x
EPS$-1.47$3.93
Book Value/Share$3.30$16.77
Revenue/Share$6.63$3.39
FCF/Share$-0.53$1.69

Profitability & Margins

MetricARWRPTGX
ROE–31.6%
ROA–29.9%
ROIC-12.4%29.6%
Operating Margin-24.2%147.1%
Net Margin–155.8%
EBT Margin-26.9%158.4%
Tax Rate-8.0%2.3%

Financial Health

MetricARWRPTGX
Current Ratio5.90x19.85x
D/E Ratio3.54x0.06x
Financial Leverage4.54x1.06x
Interest Coverage-2321.4x–
Working Capital$1.39B$1.05B

Cash Flow

MetricARWRPTGX
Operating Cash Flow-$59M$110M
Free Cash Flow-$75M$109M
Capital Spending-$16M-$760K
OCF Growth YoY-370.3%67.9%
FCF Growth YoY–71.3%
FCF/Sales-8.0%49.7%
CapEx/Sales1.7%0.3%

Operational Efficiency

MetricARWRPTGX
Asset Turnover0.44x0.19x
Receivables Turnover109.4x–
Fixed Assets Turnover2.5x66.1x
Days Sales Outstanding3 days–

Income Statement

MetricARWRPTGX
Total Revenue$936M$220M
Operating Income-$226M$323M
Net Income–$342M
R&D Expense$723M$176M

Dividend & Shareholder Information

MetricARWRPTGX
Shares Outstanding141M65M
Net Income Growth–645.5%
EPS Growth–182.7%
FAQ

ARWR vs PTGX: stock comparison and AI forecast

Which is bigger, ARWR or PTGX?

ARWR and PTGX have similar market capitalizations ($8.22B and $8.54B).

Which stock performed better over the last six months, ARWR or PTGX?

Over the last six months PTGX returned +33.6% and ARWR -25.4%.

Which one does Intratio's AI model rank higher, ARWR or PTGX?

Intratio's model scores both stocks every trading day. Sign in to see their current direction; the exact ratings and forecasts come with a plan or a free follow slot.

Compare

More comparisons

This analysis is generated automatically using our proprietary AI systems and should not be considered personalized investment advice. Past performance does not guarantee future results. Always conduct your own research and consider consulting a financial advisor before making investment decisions.