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Stock comparison · Signal date 2026-11-06

PTGX vs TGTX: stock comparison and AI forecast

Protagonist Therapeutics, Inc (PTGX) and Tg Therapeutics, Inc. (TGTX) compared on price performance, valuation, profitability and the daily AI forecast. · Alpha · vs market

Share
Nasdaq · Pharmaceutical Preparations

PTGX Protagonist Therapeutics, Inc

Market Cap
$8.54B
P/E Ratio
33.6x
Size
mid-cap
AI Forecast
Full analysis →
Nasdaq · Pharmaceutical Preparations

TGTX Tg Therapeutics, Inc.

Price
$57.98 +34.8% · 6M
Market Cap
$9.20B
P/E Ratio
21.9x
Size
mid-cap
AI Forecast
Full analysis →
Model output

Which one does the AI model favor?

Intratio's model scores both stocks every trading day. Sign in to see their current direction; the exact ratings and forecasts come with a plan or a free follow slot.

PTGX · TGTX

Key facts

  • PTGX and TGTX have similar market capitalizations ($8.54B and $9.20B).
  • TGTX trades at 21.9 times trailing earnings, PTGX at 33.6 times.
  • PTGX turns 155.8% of its revenue into net income, against 55.2% for TGTX.
  • TGTX carries 1.71 times debt per unit of equity, against 0.06 times for PTGX.
  • Both companies share the SEC industry classification Pharmaceutical Preparations.
Fundamentals

Fundamentals side by side

Trailing twelve months.

Valuation & Market

MetricPTGXTGTX
Market Cap$8.54B$9.20B
P/E Ratio33.60x21.88x
P/B Ratio7.88x15.23x
EPS$3.93$2.65
Book Value/Share$16.77$3.81
Revenue/Share$3.39$5.04
FCF/Share$1.69$0.11

Profitability & Margins

MetricPTGXTGTX
ROE31.6%73.1%
ROA29.9%26.9%
ROIC29.6%9.9%
Gross Margin–82.4%
Operating Margin147.1%17.1%
Net Margin155.8%55.2%
EBT Margin158.4%12.7%
Tax Rate2.3%-334.5%

Financial Health

MetricPTGXTGTX
Current Ratio19.85x4.27x
Quick Ratio–3.72x
D/E Ratio0.06x1.71x
Financial Leverage1.06x2.71x
Interest Coverage–1.2x
Working Capital$1.05B$877M

Cash Flow

MetricPTGXTGTX
Operating Cash Flow$110M$18M
Free Cash Flow$109M$17M
Capital Spending-$760K-$490K
OCF Growth YoY67.9%–
FCF Growth YoY71.3%–
FCF/Sales49.7%2.2%
CapEx/Sales0.3%0.1%

Operational Efficiency

MetricPTGXTGTX
Asset Turnover0.19x0.49x
Receivables Turnover–2.0x
Inventory Turnover–0.9x
Fixed Assets Turnover66.1x–
Days Sales Outstanding–183 days
Days Inventory–383 days

Income Statement

MetricPTGXTGTX
Total Revenue$220M$800M
Operating Income$323M$136M
Net Income$342M$441M
R&D Expense$176M$226M
SG&A Expense–$296M
Cost of Goods Sold–$141M

Dividend & Shareholder Information

MetricPTGXTGTX
Shares Outstanding65M159M
Net Income Growth645.5%630.2%
EPS Growth182.7%846.4%
FAQ

PTGX vs TGTX: stock comparison and AI forecast

Which is bigger, PTGX or TGTX?

PTGX and TGTX have similar market capitalizations ($8.54B and $9.20B).

Which is cheaper on earnings, PTGX or TGTX?

TGTX trades at 21.9 times trailing earnings, PTGX at 33.6 times.

Which one does Intratio's AI model rank higher, PTGX or TGTX?

Intratio's model scores both stocks every trading day. Sign in to see their current direction; the exact ratings and forecasts come with a plan or a free follow slot.

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This analysis is generated automatically using our proprietary AI systems and should not be considered personalized investment advice. Past performance does not guarantee future results. Always conduct your own research and consider consulting a financial advisor before making investment decisions.