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Model output · Signal date Oct. 16, 2026

Daily SignalsNeutral

2758 companies scored · Total · absolute moveSwitch to Alpha · 30D 90D

Signal date 2026-10-16 Cut-offs from the 2026-10-16 run
Companies scored 2758 IC ≥ 0 · market cap ≥ $100M
Median forecast +0.74% Total · 30D
Long–short spread +2.79% Strong Buy minus Strong Sell, mean
Median IC 0.17 Spearman · 30D
Rating changes ▲ 239 ▼ 400 vs the previous run
Cross-section

Distribution of the day's forecasts

30D Total forecasts of every company scored, cut into five relative ratings at the 15th, 35th, 65th and 85th percentiles (dashed lines).

Signals · Neutral

50 companies

Sorted by 30D forecast ↓

# Ticker Sector IC Mkt cap Rating 30D 90D Δ
1 HURATuHURA Biosciences, Inc./NV Life Sciences 0.01 $107M Neutral +1.13% +3.84% ▼ 1
2 WVEWave Life Sciences, Inc. Life Sciences 0.24 $617M Neutral +1.13% +3.32% ·
3 IRWDIRONWOOD PHARMACEUTICALS INC Life Sciences 0.21 $578M Neutral +1.12% +3.56% ·
4 TRLVTrulieve Cannabis Corp. Life Sciences 0.02 $1.9B Neutral +1.12% +3.23% ▼ 1
5 ANABANAPTYSBIO, INC Life Sciences 0.29 $1.4B Neutral +1.11% +3.15% ·
6 TLXTelix Pharmaceuticals Ltd Life Sciences 0.48 $3.6B Neutral +1.10% +3.17% ▼ 1
7 ACBAURORA CANNABIS INC Life Sciences -0.01 $253M Neutral +1.09% +3.25% ▼ 1
8 GMABGENMAB A/S Life Sciences 0.09 $23.8B Neutral +1.08% +3.11% ·
9 QDELQuidelOrtho Corp Life Sciences 0.09 $885M Neutral +1.06% +3.58% ·
10 CYRXCryoport, Inc. Life Sciences 0.31 $853M Neutral +1.04% +3.28% ·
11 AMRXAmneal Pharmaceuticals, Inc. Life Sciences 0.15 $6.1B Neutral +1.02% +2.91% ·
12 KROSKeros Therapeutics, Inc. Life Sciences 0.26 $211M Neutral +1.00% +3.03% ·
13 HRMYHarmony Biosciences Holdings, Inc. Life Sciences 0.35 $2.2B Neutral +0.99% +2.78% ·
14 NRIXNurix Therapeutics, Inc. Life Sciences 0.37 $2.5B Neutral +0.97% +3.01% ·
15 SIGASIGA TECHNOLOGIES INC Life Sciences 0.35 $228M Neutral +0.95% +2.73% ·
16 BBIOBridgeBio Pharma, Inc. Life Sciences 0.21 $13.0B Neutral +0.93% +2.87% ·
17 SABSSAB Biotherapeutics, Inc. Life Sciences 0.30 $230M Neutral +0.93% +2.88% ·
18 VTVTvTv Therapeutics Inc. Life Sciences 0.17 $329M Neutral +0.93% +2.89% ·
19 SUPNSUPERNUS PHARMACEUTICALS, INC. Life Sciences 0.15 $2.2B Neutral +0.92% +2.66% ▼ 1
20 NBPNovaBridge Biosciences Life Sciences 0.39 $145M Neutral +0.90% +3.01% ·
21 CGENCOMPUGEN LTD Life Sciences 0.17 $185M Neutral +0.89% +2.97% ·
22 AGIOAGIOS PHARMACEUTICALS, INC. Life Sciences 0.04 $1.9B Neutral +0.88% +2.55% ·
23 MGTXMeiraGTx Holdings plc Life Sciences 0.19 $891M Neutral +0.87% +2.94% ·
24 AMRNAMARIN CORP PLC\UK Life Sciences 0.13 $238M Neutral +0.85% +2.46% ·
25 HCMHUTCHMED (China) Ltd Life Sciences -0.06 $2.5B Neutral +0.85% +2.62% ·
26 MRKMerck & Co., Inc. Life Sciences 0.15 $360.1B Neutral +0.85% +2.37% ▲ 1
27 BHCBausch Health Companies Inc. Life Sciences 0.28 $2.4B Neutral +0.84% +2.68% ·
28 RIGLRIGEL PHARMACEUTICALS INC Life Sciences 0.13 $859M Neutral +0.82% +2.57% ·
29 INSMINSMED Inc Life Sciences 0.17 $21.0B Neutral +0.78% +2.37% ·
30 NAGENiagen Bioscience, Inc. Life Sciences 0.37 $197M Neutral +0.77% +2.65% ·
31 HALOHALOZYME THERAPEUTICS, INC. Life Sciences 0.12 $13.8B Neutral +0.76% +2.34% ·
32 QGENQIAGEN N.V. Life Sciences 0.00 $10.0B Neutral +0.76% +2.32% ·
33 INDPIndaptus Therapeutics, Inc. Life Sciences 0.26 $350M Neutral +0.72% +2.57% ▲ 2
34 IPHAInnate Pharma SA Life Sciences 0.13 $134M Neutral +0.72% +2.53% ▼ 1
35 ALNYALNYLAM PHARMACEUTICALS, INC. Life Sciences 0.32 $31.0B Neutral +0.71% +2.21% ·
36 TLRYTilray Brands, Inc. Life Sciences -0.01 $414M Neutral +0.69% +2.43% ·
37 ARDXARDELYX, INC. Life Sciences 0.27 $770M Neutral +0.68% +2.30% ·
38 KRYSKrystal Biotech, Inc. Life Sciences -0.04 $9.4B Neutral +0.68% +2.24% ·
39 MSLESatellos Bioscience Inc. Life Sciences 0.11 $138M Neutral +0.66% +2.35% ·
40 VRDNViridian Therapeutics, Inc.\DE Life Sciences 0.35 $2.2B Neutral +0.63% +2.22% ▼ 1
41 COAGHemab Therapeutics Holdings, Inc. Life Sciences -0.30 $1.4B Neutral +0.61% +2.18% ·
42 CRMDCorMedix Inc. Life Sciences 0.06 $566M Neutral +0.61% +2.18% ·
43 LKFTLakefront Biotherapeutics NV Life Sciences 0.23 $2.0B Neutral +0.60% +2.07% ▲ 1
44 BMRNBIOMARIN PHARMACEUTICAL INC Life Sciences 0.16 $10.6B Neutral +0.56% +1.92% ▲ 1
45 RPRXRoyalty Pharma plc Life Sciences 0.20 $26.9B Neutral +0.55% +1.82% ·
46 ELANElanco Animal Health Inc Life Sciences 0.33 $11.8B Neutral +0.54% +2.02% ▲ 1
47 MDWDMediWound Ltd. Life Sciences 0.09 $152M Neutral +0.54% +1.95% ·
48 VCELVericel Corp Life Sciences 0.21 $2.1B Neutral +0.54% +1.96% ·
49 DBVTDBV Technologies S.A. Life Sciences 0.38 $536M Neutral +0.52% +1.92% ▲ 1
50 VRTXVERTEX PHARMACEUTICALS INC / MA Life Sciences -0.05 $126.7B Neutral +0.52% +1.84% ·
Since the previous run

Rating changes

▲ 239▼ 400
Which companies were upgraded or downgraded is part of the paid plans.
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Methodology

Ratings are relative: the forecasts of the latest complete daily run (2026-10-16) are ranked and cut at the 15th, 35th, 65th and 85th percentiles, so Strong Sell is the bottom 15%, Sell the next 20%, Neutral the middle 30%, Buy the next 20% and Strong Buy the top 15%. Expected absolute price move over the horizon, market included. This is the number a price target is built from. IC is the company's Spearman information coefficient between its past forecasts and the realised returns at the selected horizon; IC-weighted ranking multiplies each forecast by its IC (negative IC counts as zero). Δ is the rating move since the company's previous signal, in rating steps. Each company shows its latest signal, including one from a run still in progress; every signal is rated against the cut-offs above. Quantitative research output, not investment advice.