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Stock comparison · Signal date 2026-11-06

MDGL vs PTGX: stock comparison and AI forecast

Madrigal Pharmaceuticals, Inc. (MDGL) and Protagonist Therapeutics, Inc (PTGX) compared on price performance, valuation, profitability and the daily AI forecast. · Alpha · vs market

Share
Nasdaq · Pharmaceutical Preparations

MDGL Madrigal Pharmaceuticals, Inc.

Price
$400.10 -25.2% · 6M
Market Cap
$9.24B
P/E Ratio
–
Size
mid-cap
AI Forecast
Full analysis →
Nasdaq · Pharmaceutical Preparations

PTGX Protagonist Therapeutics, Inc

Market Cap
$8.54B
P/E Ratio
33.6x
Size
mid-cap
AI Forecast
Full analysis →
Model output

Which one does the AI model favor?

Intratio's model scores both stocks every trading day. Sign in to see their current direction; the exact ratings and forecasts come with a plan or a free follow slot.

MDGL · PTGX

Key facts

  • MDGL and PTGX have similar market capitalizations ($9.24B and $8.54B).
  • PTGX turns 155.8% of its revenue into net income, against -8.7% for MDGL.
  • MDGL carries 1.29 times debt per unit of equity, against 0.06 times for PTGX.
  • Both companies share the SEC industry classification Pharmaceutical Preparations.
Fundamentals

Fundamentals side by side

Trailing twelve months.

Valuation & Market

MetricMDGLPTGX
Market Cap$9.24B$8.54B
P/E Ratio–33.60x
P/B Ratio14.74x7.88x
EPS$-5.96$3.93
Book Value/Share$27.14$16.77
Revenue/Share$76.96$3.39
FCF/Share$-7.30$1.69

Profitability & Margins

MetricMDGLPTGX
ROE-24.8%31.6%
ROA-10.8%29.9%
ROIC-15.6%29.6%
Operating Margin-8.6%147.1%
Net Margin-8.7%155.8%
EBT Margin-7.9%158.4%
Tax Rate–2.3%

Financial Health

MetricMDGLPTGX
Current Ratio3.05x19.85x
Quick Ratio2.78x–
D/E Ratio1.29x0.06x
Financial Leverage2.29x1.06x
Interest Coverage-24.1x–
Working Capital$933M$1.05B

Cash Flow

MetricMDGLPTGX
Operating Cash Flow-$157M$110M
Free Cash Flow-$169M$109M
Capital Spending-$12M-$760K
OCF Growth YoY–67.9%
FCF Growth YoY–71.3%
FCF/Sales-9.5%49.7%
CapEx/Sales0.7%0.3%

Operational Efficiency

MetricMDGLPTGX
Asset Turnover1.24x0.19x
Receivables Turnover7.8x–
Fixed Assets Turnover127.4x66.1x
Days Sales Outstanding47 days–

Income Statement

MetricMDGLPTGX
Total Revenue$1.78B$220M
Operating Income-$153M$323M
Net Income-$155M$342M
R&D Expense$486M$176M
SG&A Expense$1.06B–

Dividend & Shareholder Information

MetricMDGLPTGX
Shares Outstanding23M65M
Net Income Growth–645.5%
EPS Growth–182.7%
FAQ

MDGL vs PTGX: stock comparison and AI forecast

Which is bigger, MDGL or PTGX?

MDGL and PTGX have similar market capitalizations ($9.24B and $8.54B).

Which one does Intratio's AI model rank higher, MDGL or PTGX?

Intratio's model scores both stocks every trading day. Sign in to see their current direction; the exact ratings and forecasts come with a plan or a free follow slot.

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This analysis is generated automatically using our proprietary AI systems and should not be considered personalized investment advice. Past performance does not guarantee future results. Always conduct your own research and consider consulting a financial advisor before making investment decisions.