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Model output · Signal date Oct. 16, 2026

Daily SignalsNeutral

2761 companies scored · Total · absolute moveSwitch to Alpha · 30D 90D

Signal date 2026-10-16 Cut-offs from the 2026-10-16 run
Companies scored 2761 IC ≥ 0 · market cap ≥ $100M
Median forecast +2.40% Total · 90D
Long–short spread +6.35% Strong Buy minus Strong Sell, mean
Median IC 0.27 Spearman · 90D
Rating changes ▲ 165 ▼ 376 vs the previous run
Cross-section

Distribution of the day's forecasts

90D Total forecasts of every company scored, cut into five relative ratings at the 15th, 35th, 65th and 85th percentiles (dashed lines).

Signals · Neutral

56 companies

Sorted by 90D forecast ↓

# Ticker Sector IC Mkt cap Rating 30D 90D Δ
1 CYRXCryoport, Inc. Life Sciences 0.29 $853M Neutral +1.04% +3.27% ·
2 ACBAURORA CANNABIS INC Life Sciences 0.16 $253M Neutral +1.09% +3.26% ▼ 1
3 WVEWave Life Sciences, Inc. Life Sciences 0.18 $629M Neutral +1.10% +3.26% ·
4 ACOGAlpha Cognition Inc. Life Sciences 0.62 $184M Neutral +1.12% +3.24% ▼ 1
5 TRLVTrulieve Cannabis Corp. Life Sciences 0.56 $2.0B Neutral +1.12% +3.24% ▼ 1
6 GILDGILEAD SCIENCES, INC. Life Sciences 0.10 $195.1B Neutral +1.19% +3.22% ▼ 1
7 ASNDAscendis Pharma A/S Life Sciences 0.00 $14.8B Neutral +1.19% +3.21% ▼ 1
8 LXRXLEXICON PHARMACEUTICALS, INC. Life Sciences 0.44 $734M Neutral +1.04% +3.19% ▼ 1
9 PTCTPTC THERAPEUTICS, INC. Life Sciences 0.12 $5.1B Neutral +1.15% +3.18% ▼ 1
10 VNDAVanda Pharmaceuticals Inc. Life Sciences 0.28 $256M Neutral +1.13% +3.16% ·
11 ANABANAPTYSBIO, INC Life Sciences 0.27 $1.4B Neutral +1.11% +3.15% ·
12 TLXTelix Pharmaceuticals Ltd Life Sciences 0.15 $3.6B Neutral +1.07% +3.13% ▼ 1
13 RGENREPLIGEN CORP Life Sciences 0.62 $10.4B Neutral +1.01% +3.10% ·
14 NRIXNurix Therapeutics, Inc. Life Sciences 0.27 $2.6B Neutral +1.02% +3.09% ·
15 GMABGENMAB A/S Life Sciences 0.02 $24.3B Neutral +1.06% +3.06% ·
16 PBYIPUMA BIOTECHNOLOGY, INC. Life Sciences 0.01 $543M Neutral +1.07% +2.96% ·
17 AMRXAmneal Pharmaceuticals, Inc. Life Sciences 0.48 $6.1B Neutral +1.02% +2.91% ·
18 NBPNovaBridge Biosciences Life Sciences 0.18 $149M Neutral +0.85% +2.88% ·
19 BBIOBridgeBio Pharma, Inc. Life Sciences 0.08 $13.0B Neutral +0.93% +2.87% ·
20 KROSKeros Therapeutics, Inc. Life Sciences 0.15 $220M Neutral +0.92% +2.87% ·
21 IRWDIRONWOOD PHARMACEUTICALS INC Life Sciences 0.22 $623M Neutral +0.83% +2.86% ·
22 OMEROMEROS CORP Life Sciences 0.15 $1.4B Neutral +0.81% +2.81% ·
23 VTVTvTv Therapeutics Inc. Life Sciences 0.14 $342M Neutral +0.88% +2.78% ▼ 1
24 SABSSAB Biotherapeutics, Inc. Life Sciences 0.15 $236M Neutral +0.87% +2.76% ·
25 HRMYHarmony Biosciences Holdings, Inc. Life Sciences 0.49 $2.2B Neutral +0.97% +2.74% ·
26 SIGASIGA TECHNOLOGIES INC Life Sciences 0.47 $229M Neutral +0.94% +2.73% ·
27 BHCBausch Health Companies Inc. Life Sciences 0.51 $2.4B Neutral +0.84% +2.68% ·
28 CGENCOMPUGEN LTD Life Sciences 0.31 $197M Neutral +0.77% +2.67% ·
29 NIKANIKA PHARMACEUTICALS, INC Life Sciences 0.17 $431M Neutral -0.80% +2.67% new
30 MRKMerck & Co., Inc. Life Sciences 0.21 $358.2B Neutral +0.96% +2.62% ▲ 1
31 TGTXTG THERAPEUTICS, INC. Life Sciences 0.43 $8.9B Neutral +0.88% +2.58% ·
32 MGTXMeiraGTx Holdings plc Life Sciences 0.31 $950M Neutral +0.73% +2.55% ·
33 SUPNSUPERNUS PHARMACEUTICALS, INC. Life Sciences 0.10 $2.3B Neutral +0.86% +2.55% ▼ 1
34 AGIOAGIOS PHARMACEUTICALS, INC. Life Sciences 0.14 $1.9B Neutral +0.87% +2.52% ·
35 INDPIndaptus Therapeutics, Inc. Life Sciences 0.09 $380M Neutral +0.70% +2.51% ▲ 1
36 IPHAInnate Pharma SA Life Sciences 0.15 $139M Neutral +0.71% +2.50% ▼ 1
37 AMRNAMARIN CORP PLC\UK Life Sciences 0.05 $238M Neutral +0.85% +2.46% ·
38 RIGLRIGEL PHARMACEUTICALS INC Life Sciences 0.05 $883M Neutral +0.75% +2.43% ·
39 HCMHUTCHMED (China) Ltd Life Sciences 0.14 $2.5B Neutral +0.73% +2.39% ·
40 NAGENiagen Bioscience, Inc. Life Sciences 0.59 $204M Neutral +0.67% +2.38% ·
41 TLRYTilray Brands, Inc. Life Sciences 0.15 $437M Neutral +0.67% +2.37% ·
42 HALOHALOZYME THERAPEUTICS, INC. Life Sciences 0.31 $13.8B Neutral +0.76% +2.35% ·
43 ARDXARDELYX, INC. Life Sciences 0.39 $770M Neutral +0.68% +2.30% ·
44 MSLESatellos Bioscience Inc. Life Sciences 0.52 $146M Neutral +0.64% +2.29% ·
45 VRDNViridian Therapeutics, Inc.\DE Life Sciences 0.46 $2.2B Neutral +0.67% +2.29% ▼ 1
46 INSMINSMED Inc Life Sciences 0.43 $21.7B Neutral +0.72% +2.25% ·
47 LKFTLakefront Biotherapeutics NV Life Sciences 0.38 $2.0B Neutral +0.68% +2.23% ·
48 ALNYALNYLAM PHARMACEUTICALS, INC. Life Sciences 0.56 $31.0B Neutral +0.71% +2.22% ·
49 CRMDCorMedix Inc. Life Sciences 0.18 $566M Neutral +0.61% +2.19% ·
50 COAGHemab Therapeutics Holdings, Inc. Life Sciences 0.46 $1.4B Neutral +0.61% +2.18% ·
1–50 of 56 Previous Next
Since the previous run

Rating changes

▲ 165▼ 376
Which companies were upgraded or downgraded is part of the paid plans.
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Every company's rating, its 30- and 90-day forecasts, the forecast and IC-weighted rankings, the daily rating changes and CSV export.

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Methodology

Ratings are relative: the forecasts of the latest complete daily run (2026-10-16) are ranked and cut at the 15th, 35th, 65th and 85th percentiles, so Strong Sell is the bottom 15%, Sell the next 20%, Neutral the middle 30%, Buy the next 20% and Strong Buy the top 15%. Expected absolute price move over the horizon, market included. This is the number a price target is built from. IC is the company's Spearman information coefficient between its past forecasts and the realised returns at the selected horizon; IC-weighted ranking multiplies each forecast by its IC (negative IC counts as zero). Δ is the rating move since the company's previous signal, in rating steps. Each company shows its latest signal, including one from a run still in progress; every signal is rated against the cut-offs above. Quantitative research output, not investment advice.