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Model output · Signal date 2026-11-06

Puma Biotechnology, Inc. (PBYI) Stock Forecast Nov. 6, 2026

Analysis updated on Nov. 6, 2026 (UTC) · Alpha · vs marketSwitch to Total · Nasdaq

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Rating · 90D Unlock rating and forecasts
90-day forecast Sign up free to reveal
30-day forecast Alpha
Rank in coverage of 5150 stocks scored
Rank correlation · 90D -9.0% Spearman, 357 dates
Market Cap $426M small-cap · #60 of 60 peers
Summary

Puma Biotechnology, Inc. (PBYI) stock forecast summary

Our AI scores Puma Biotechnology, Inc. every trading day against every stock it covers. Create a free account and follow it to see its rating and price target.

Puma Biotechnology, Inc. is a small-cap company with a market capitalization of $426M. It ranks number 60 by market capitalization among the 60 Pharmaceutical Preparations issuers in our coverage with a current forecast.

For PBYI, the Spearman rank correlation between our 90-day forecasts and the returns that followed is -9.0%, measured on 357 forecast dates between 2022-08-19 and 2026-08-07 on this stock's own recent history. A rank correlation runs from -100% to +100%: it measures whether higher forecasts were followed by higher returns, and a value near zero or below means the model has shown little skill on this stock. On the 30-day forecasts the same correlation is 12.0%, measured on 400 forecast dates between 2022-08-19 and 2026-10-07. Across our coverage, the out-of-sample test on 4629 stocks from 2025-01-06 to 2026-08-04 produced a positive net return in 92.9% of rebalance periods (factor-neutral book, net of estimated costs). Full backtest report

Expected return relative to the market over the horizon: a positive alpha means the model expects the stock to beat the market, whatever the market does. Ratings: strong buy ≥ +3.1%, buy ≥ +1.5%, sell < -0.5%, strong sell < -1.8% (top 15%, next 20%, middle 30%, next 20%, bottom 15% of the 2026-11-06 signals)

A free account shows the exact forecast, rating and rank of 3 tickers you follow, PBYI included.

Price

PBYI price chart and AI forecast

PBYI
Cross-section · 2026-11-06

How PBYI ranks among 5150 stocks

90D Alpha forecasts of every company scored, cut into five relative ratings at the 15th, 35th, 65th and 85th percentiles (dashed lines).

Fundamentals · 2026-06-30

Puma Biotechnology, Inc. (PBYI) fundamentals

Trailing twelve months. The industry median and the rank (1 = highest) are taken over the Pharmaceutical Preparations peers listed below that report each metric.

Valuation & Market

MetricPBYIIndustry medianRank
Market Cap $426M $12.65B 60/60
P/E Ratio 12.69x 34.93x 26/33
P/B Ratio 3.07x 7.13x 38/43
EPS $0.65 – –
Book Value/Share $2.68 – –
Revenue/Share $4.48 – –
FCF/Share $0.80 – –

Profitability & Margins

MetricPBYIIndustry medianRank
ROE 19.3% 5.5% 14/39
ROA 13.9% 2.0% 13/43
ROIC 21.3% 1.4% 7/45
Gross Margin 74.8% 82.1% 22/36
Operating Margin 13.2% 11.5% 18/39
Net Margin 11.6% 8.0% 17/36
EBT Margin 13.5% 13.1% 23/46
Tax Rate 13.7% – –

Financial Health

MetricPBYIIndustry medianRank
Current Ratio 2.91x 2.49x 26/58
Quick Ratio 2.64x 1.64x 12/43
D/E Ratio 0.39x 1.21x 32/48
Financial Leverage 1.39x 2.06x 31/48
Interest Coverage 10.0x 1.2x 8/34
Working Capital $95M $911M 52/58

Cash Flow

MetricPBYIIndustry medianRank
Operating Cash Flow $41M $199M 36/59
Free Cash Flow $41M $196M 31/50
Capital Spending $10K -$39M 1/50
OCF Growth YoY -7.2% -0.6% 24/35
FCF Growth YoY -6.9% 0.0% 25/33
FCF/Sales 17.8% 18.2% 22/42
CapEx/Sales 0.0% 2.4% 42/42

Operational Efficiency

MetricPBYIIndustry medianRank
Asset Turnover 1.20x 0.49x 5/39
Receivables Turnover 6.8x 5.3x 10/37
Inventory Turnover 4.4x 1.7x 6/35
Fixed Assets Turnover 2245.1x 8.1x 1/41
Days Sales Outstanding 54 days 69 days 28/37
Days Inventory 84 days 216 days 30/35
Payables Period 19 days 118 days 24/25
Cash Conversion Cycle 118 days 185 days 14/23

Income Statement

MetricPBYIIndustry medianRank
Total Revenue $231M $2.87B 43/46
Operating Income $30M $64M 27/51
Net Income $27M $51M 25/47
R&D Expense $71M $568M 56/58
SG&A Expense $71M $1.43B 41/41
Cost of Goods Sold $58M $1.87B 32/37

Dividend & Shareholder Information

MetricPBYIIndustry medianRank
Shares Outstanding 52M – –
Net Income Growth -44.9% 5.5% 18/24
EPS Growth -21.7% 8.0% 18/25

Balance Sheet Highlights (USD millions)

Total Current Assets$145M75.2% of assets
Cash & Short-term Investments$37M18.9% of assets
Accounts Receivable$34M17.7% of assets
Inventory$13M6.9% of assets
Total Liabilities$54M28.1% of assets
Short-term Debt$47M24.2% of assets
Quarterly Financial Reports

PBYI quarterly financials and insider trading

Industry Peers · Pharmaceutical Preparations

Puma Biotechnology, Inc. (PBYI) industry peers

Companies classified under the same SEC industry code as Puma Biotechnology, Inc. (Pharmaceutical Preparations): 60 common-stock issuers with a forecast this week, one row per issuer, largest first. This is a classification match, not a curated list of competitors.

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Company 90-Day AI Forecast (Alpha) Market Cap P/E Ratio P/B Ratio
PBYI Puma Biotechnology, Inc. $426M 12.7x 3.1x
LLY Eli Lilly & Co $1.28T 44.3x 130.6x
JNJ Johnson & Johnson $664.95B 42.0x 8.2x
ABBV Abbvie Inc. $514.78B 44.6x –
MRK Merck & Co., Inc. $362.01B 151.3x 8.1x
NVS Novartis Ag $310.17B 9.8x –
AZN Astrazeneca Plc $288.97B 13.5x –
ABT Abbott Laboratories $191.15B 38.8x 3.8x
NVO Novo Nordisk A S $179.14B 3.0x –
PFE Pfizer Inc $167.51B 37.2x 1.9x
VRTX Vertex Pharmaceuticals Inc / Ma $137.50B 34.9x 6.6x
BMY Bristol Myers Squibb Co $127.02B 13.8x 5.4x
SNY Sanofi $115.97B – –
GSK Gsk Plc $101.70B 5.6x –
REGN Regeneron Pharmaceuticals, Inc. $93.11B 20.0x 2.8x
TAK Takeda Pharmaceutical Co Ltd $66.19B 6.4x –
TEVA Teva Pharmaceutical Industries Ltd $49.65B 41.0x 6.2x
ONC Beone Medicines Ltd. $46.26B 1130.5x 8.0x
GMAB Genmab A/S $34.50B 2.2x –
ZTS Zoetis Inc. $33.93B 14.0x 10.3x
RPRX Royalty Pharma Plc $28.82B 47.1x 4.2x
ROIV Roivant Sciences Ltd. $26.45B – 6.3x
INSM Insmed Inc $25.10B – 34.6x
UTHR United Therapeutics Corp $24.11B 21.2x 3.8x
VTRS Viatris Inc $22.87B – –
ALNY Alnylam Pharmaceuticals, Inc. $20.89B 7.3x 5.8x
ASND Ascendis Pharma A/S $16.86B – –
JAZZ Jazz Pharmaceuticals Plc $15.24B 77.5x 3.6x
BBIO Bridgebio Pharma, Inc. $14.47B – –
SMMT Summit Therapeutics Inc. $13.03B – 23.1x
ELAN Elanco Animal Health Inc $12.86B – 1.9x
RDY Dr Reddys Laboratories Ltd $12.44B 16.4x –
BMRN Biomarin Pharmaceutical Inc $10.85B 560.3x 1.7x
MDGL Madrigal Pharmaceuticals, Inc. $9.24B – 14.7x
TGTX Tg Therapeutics, Inc. $9.20B 21.9x 15.2x
SYRE Spyre Therapeutics, Inc. $9.16B – 8.7x
PTGX Protagonist Therapeutics, Inc $8.54B 33.6x 7.9x
ARWR Arrowhead Pharmaceuticals, Inc. $8.22B – 17.7x
CORT Corcept Therapeutics Inc $7.87B 43.6x 9.4x
PRAX Praxis Precision Medicines, Inc. $7.75B – 5.8x
RYTM Rhythm Pharmaceuticals, Inc. $7.73B – 87.9x
ALKS Alkermes Plc. $7.70B 44.6x 4.1x
ABVX Abivax S.A. $7.50B – –
CYTK Cytokinetics Inc $7.46B – –
KNSA Kiniksa Pharmaceuticals International, Plc $6.94B 81.8x 9.8x
AXSM Axsome Therapeutics, Inc. $6.93B – 65.8x
ORKA Oruka Therapeutics, Inc. $6.81B – 6.1x
IONS Ionis Pharmaceuticals Inc $6.55B – 14.9x
AMRX Amneal Pharmaceuticals, Inc. $6.43B 61.0x –
MIRM Mirum Pharmaceuticals, Inc. $6.07B – –
BLTE Belite Bio, Inc $6.07B – 7.9x
LGND Ligand Pharmaceuticals Inc $5.98B 114.1x 6.2x
MANE Veradermics, Inc $5.80B – 7.1x
SUPN Supernus Pharmaceuticals, Inc. $5.56B – 5.2x
COGT Cogent Biosciences, Inc. $5.49B – 10.6x
PTCT Ptc Therapeutics, Inc. $5.47B – –
EWTX Edgewise Therapeutics, Inc. $4.89B 5.4x 3.0x
DNTH Dianthus Therapeutics, Inc. /De/ $4.64B – 3.7x
ERAS Erasca, Inc. $4.64B – 12.8x
TVTX Travere Therapeutics, Inc. $4.44B – 196.6x

Where PBYI sits on the market map

Life Sciences · Pharmaceutical Preparations
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News

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FAQ

Puma Biotechnology, Inc. (PBYI) stock forecast FAQ

What is the Puma Biotechnology, Inc. (PBYI) stock forecast?

Our AI scores Puma Biotechnology, Inc. every trading day against every stock it covers. Create a free account and follow it to see its rating and price target.

How accurate are Puma Biotechnology, Inc. stock predictions?

For PBYI, the Spearman rank correlation between our 90-day forecasts and the returns that followed is -9.0%, measured on 357 forecast dates between 2022-08-19 and 2026-08-07 on this stock's own recent history. A rank correlation runs from -100% to +100%: it measures whether higher forecasts were followed by higher returns, and a value near zero or below means the model has shown little skill on this stock. On the 30-day forecasts the same correlation is 12.0%, measured on 400 forecast dates between 2022-08-19 and 2026-10-07. Across our coverage, the out-of-sample test on 4629 stocks from 2025-01-06 to 2026-08-04 produced a positive net return in 92.9% of rebalance periods (factor-neutral book, net of estimated costs). Full backtest report

How often are Puma Biotechnology, Inc. forecasts updated?

Puma Biotechnology, Inc. forecasts are refreshed on trading days as the daily model run completes. The forecast on this page was produced on Nov. 6, 2026.

Which companies are Puma Biotechnology, Inc.'s industry peers?

60 issuers in our coverage, PBYI included, share the SEC industry code Pharmaceutical Preparations. The largest are: Eli Lilly & Co (LLY), Johnson & Johnson (JNJ), Abbvie Inc. (ABBV), Merck & Co., Inc. (MRK), Novartis Ag (NVS), Astrazeneca Plc (AZN).

This analysis is generated automatically using our proprietary AI systems and should not be considered personalized investment advice. Past performance does not guarantee future results. Always conduct your own research and consider consulting a financial advisor before making investment decisions.