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Model output · Signal date 2026-11-06

Rhythm Pharmaceuticals, Inc. (RYTM) Stock Forecast Nov. 6, 2026

Analysis updated on Nov. 6, 2026 (UTC) · Alpha · vs marketSwitch to Total · Nasdaq

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Rating · 90D Unlock rating and forecasts
90-day forecast Sign up free to reveal
30-day forecast Alpha
Rank in coverage of 5150 stocks scored
Rank correlation · 90D 32.0% Spearman, 357 dates
Market Cap $7.73B mid-cap · #40 of 60 peers
Summary

Rhythm Pharmaceuticals, Inc. (RYTM) stock forecast summary

Our AI scores Rhythm Pharmaceuticals, Inc. every trading day against every stock it covers. Create a free account and follow it to see its rating and price target.

Rhythm Pharmaceuticals, Inc. is a mid-cap company with a market capitalization of $7.73B. It ranks number 40 by market capitalization among the 60 Pharmaceutical Preparations issuers in our coverage with a current forecast.

For RYTM, the Spearman rank correlation between our 90-day forecasts and the returns that followed is 32.0%, measured on 357 forecast dates between 2022-08-19 and 2026-08-07 on this stock's own recent history. A rank correlation runs from -100% to +100%: it measures whether higher forecasts were followed by higher returns, and a value near zero or below means the model has shown little skill on this stock. On the 30-day forecasts the same correlation is -1.0%, measured on 400 forecast dates between 2022-08-19 and 2026-10-07. Across our coverage, the out-of-sample test on 4629 stocks from 2025-01-06 to 2026-08-04 produced a positive net return in 92.9% of rebalance periods (factor-neutral book, net of estimated costs). Full backtest report

Expected return relative to the market over the horizon: a positive alpha means the model expects the stock to beat the market, whatever the market does. Ratings: strong buy ≥ +3.1%, buy ≥ +1.5%, sell < -0.5%, strong sell < -1.8% (top 15%, next 20%, middle 30%, next 20%, bottom 15% of the 2026-11-06 signals)

A free account shows the exact forecast, rating and rank of 3 tickers you follow, RYTM included.

Price

RYTM price chart and AI forecast

RYTM
Cross-section · 2026-11-06

How RYTM ranks among 5150 stocks

90D Alpha forecasts of every company scored, cut into five relative ratings at the 15th, 35th, 65th and 85th percentiles (dashed lines).

Fundamentals · 2026-09-30

Rhythm Pharmaceuticals, Inc. (RYTM) fundamentals

Trailing twelve months. The industry median and the rank (1 = highest) are taken over the Pharmaceutical Preparations peers listed below that report each metric.

Valuation & Market

MetricRYTMIndustry medianRank
Market Cap $7.73B $12.65B 40/60
P/B Ratio 87.88x 7.50x 3/42
EPS $-2.88 – –
Book Value/Share $1.28 – –
Revenue/Share $4.08 – –

Profitability & Margins

MetricRYTMIndustry medianRank
ROE -220.3% 5.4% 37/38
ROA -43.7% 1.9% 38/42
ROIC -64.1% 1.3% 40/44
Gross Margin 88.2% 82.1% 9/36
Operating Margin -66.7% 10.3% 33/38
Net Margin -69.0% 6.3% 30/35
EBT Margin -68.5% 9.9% 41/46
Tax Rate -0.8% – –

Financial Health

MetricRYTMIndustry medianRank
Current Ratio 2.78x 2.46x 27/58
Quick Ratio 2.57x 1.64x 13/43
D/E Ratio 2.75x 1.22x 10/47
Financial Leverage 5.04x 2.12x 4/47
Interest Coverage -29.4x 1.2x 28/33
Working Capital $268M $911M 48/58

Cash Flow

MetricRYTMIndustry medianRank
Operating Cash Flow -$82M $199M 42/59

Operational Efficiency

MetricRYTMIndustry medianRank
Asset Turnover 0.63x 0.49x 14/39
Receivables Turnover 7.2x 5.3x 9/36
Inventory Turnover 1.1x 1.7x 25/35
Fixed Assets Turnover 493.4x 8.1x 2/41
Days Sales Outstanding 51 days 69 days 28/36
Days Inventory 344 days 216 days 11/35
Payables Period 118 days 124 days 13/24
Cash Conversion Cycle 277 days 197 days 10/22

Income Statement

MetricRYTMIndustry medianRank
Total Revenue $281M $2.87B 42/46
Operating Income -$187M $88M 35/50
Net Income -$194M $81M 33/46
R&D Expense $180M $603M 49/58
SG&A Expense $255M $1.49B 39/40
Cost of Goods Sold $33M $1.87B 34/37

Dividend & Shareholder Information

MetricRYTMIndustry medianRank
Shares Outstanding 69M – –

Balance Sheet Highlights (USD millions)

Total Current Assets$419M
Cash & Short-term Investments$40M12.1% of assets
Accounts Receivable$39M11.9% of assets
Inventory$31M9.5% of assets
Total Liabilities$242M73.3% of assets
Short-term Debt$140M42.5% of assets
Quarterly Financial Reports

RYTM quarterly financials and insider trading

Industry Peers · Pharmaceutical Preparations

Rhythm Pharmaceuticals, Inc. (RYTM) industry peers

Companies classified under the same SEC industry code as Rhythm Pharmaceuticals, Inc. (Pharmaceutical Preparations): 60 common-stock issuers with a forecast this week, one row per issuer, largest first. This is a classification match, not a curated list of competitors.

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Company 90-Day AI Forecast (Alpha) Market Cap P/E Ratio P/B Ratio
RYTM Rhythm Pharmaceuticals, Inc. $7.73B – 87.9x
LLY Eli Lilly & Co $1.28T 44.3x 130.6x
JNJ Johnson & Johnson $664.95B 42.0x 8.2x
ABBV Abbvie Inc. $514.78B 44.6x –
MRK Merck & Co., Inc. $362.01B 151.3x 8.1x
NVS Novartis Ag $310.17B 9.8x –
AZN Astrazeneca Plc $288.97B 13.5x –
ABT Abbott Laboratories $191.15B 38.8x 3.8x
NVO Novo Nordisk A S $179.14B 3.0x –
PFE Pfizer Inc $167.51B 37.2x 1.9x
VRTX Vertex Pharmaceuticals Inc / Ma $137.50B 34.9x 6.6x
BMY Bristol Myers Squibb Co $127.02B 13.8x 5.4x
SNY Sanofi $115.97B – –
GSK Gsk Plc $101.70B 5.6x –
REGN Regeneron Pharmaceuticals, Inc. $93.11B 20.0x 2.8x
TAK Takeda Pharmaceutical Co Ltd $66.19B 6.4x –
TEVA Teva Pharmaceutical Industries Ltd $49.65B 41.0x 6.2x
ONC Beone Medicines Ltd. $46.26B 1130.5x 8.0x
GMAB Genmab A/S $34.50B 2.2x –
ZTS Zoetis Inc. $33.93B 14.0x 10.3x
RPRX Royalty Pharma Plc $28.82B 47.1x 4.2x
ROIV Roivant Sciences Ltd. $26.45B – 6.3x
INSM Insmed Inc $25.10B – 34.6x
UTHR United Therapeutics Corp $24.11B 21.2x 3.8x
VTRS Viatris Inc $22.87B – –
ALNY Alnylam Pharmaceuticals, Inc. $20.89B 7.3x 5.8x
ASND Ascendis Pharma A/S $16.86B – –
JAZZ Jazz Pharmaceuticals Plc $15.24B 77.5x 3.6x
BBIO Bridgebio Pharma, Inc. $14.47B – –
SMMT Summit Therapeutics Inc. $13.03B – 23.1x
ELAN Elanco Animal Health Inc $12.86B – 1.9x
RDY Dr Reddys Laboratories Ltd $12.44B 16.4x –
BMRN Biomarin Pharmaceutical Inc $10.85B 560.3x 1.7x
MDGL Madrigal Pharmaceuticals, Inc. $9.24B – 14.7x
TGTX Tg Therapeutics, Inc. $9.20B 21.9x 15.2x
SYRE Spyre Therapeutics, Inc. $9.16B – 8.7x
PTGX Protagonist Therapeutics, Inc $8.54B 33.6x 7.9x
ARWR Arrowhead Pharmaceuticals, Inc. $8.22B – 17.7x
CORT Corcept Therapeutics Inc $7.87B 43.6x 9.4x
PRAX Praxis Precision Medicines, Inc. $7.75B – 5.8x
ALKS Alkermes Plc. $7.70B 44.6x 4.1x
ABVX Abivax S.A. $7.50B – –
CYTK Cytokinetics Inc $7.46B – –
KNSA Kiniksa Pharmaceuticals International, Plc $6.94B 81.8x 9.8x
AXSM Axsome Therapeutics, Inc. $6.93B – 65.8x
ORKA Oruka Therapeutics, Inc. $6.81B – 6.1x
IONS Ionis Pharmaceuticals Inc $6.55B – 14.9x
AMRX Amneal Pharmaceuticals, Inc. $6.43B 61.0x –
MIRM Mirum Pharmaceuticals, Inc. $6.07B – –
BLTE Belite Bio, Inc $6.07B – 7.9x
LGND Ligand Pharmaceuticals Inc $5.98B 114.1x 6.2x
MANE Veradermics, Inc $5.80B – 7.1x
SUPN Supernus Pharmaceuticals, Inc. $5.56B – 5.2x
COGT Cogent Biosciences, Inc. $5.49B – 10.6x
PTCT Ptc Therapeutics, Inc. $5.47B – –
EWTX Edgewise Therapeutics, Inc. $4.89B 5.4x 3.0x
DNTH Dianthus Therapeutics, Inc. /De/ $4.64B – 3.7x
ERAS Erasca, Inc. $4.64B – 12.8x
TVTX Travere Therapeutics, Inc. $4.44B – 196.6x
LEGN Legend Biotech Corp $4.17B – –

Where RYTM sits on the market map

Life Sciences · Pharmaceutical Preparations
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News

Rhythm Pharmaceuticals, Inc. (RYTM) stock news

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FAQ

Rhythm Pharmaceuticals, Inc. (RYTM) stock forecast FAQ

What is the Rhythm Pharmaceuticals, Inc. (RYTM) stock forecast?

Our AI scores Rhythm Pharmaceuticals, Inc. every trading day against every stock it covers. Create a free account and follow it to see its rating and price target.

How accurate are Rhythm Pharmaceuticals, Inc. stock predictions?

For RYTM, the Spearman rank correlation between our 90-day forecasts and the returns that followed is 32.0%, measured on 357 forecast dates between 2022-08-19 and 2026-08-07 on this stock's own recent history. A rank correlation runs from -100% to +100%: it measures whether higher forecasts were followed by higher returns, and a value near zero or below means the model has shown little skill on this stock. On the 30-day forecasts the same correlation is -1.0%, measured on 400 forecast dates between 2022-08-19 and 2026-10-07. Across our coverage, the out-of-sample test on 4629 stocks from 2025-01-06 to 2026-08-04 produced a positive net return in 92.9% of rebalance periods (factor-neutral book, net of estimated costs). Full backtest report

How often are Rhythm Pharmaceuticals, Inc. forecasts updated?

Rhythm Pharmaceuticals, Inc. forecasts are refreshed on trading days as the daily model run completes. The forecast on this page was produced on Nov. 6, 2026.

Which companies are Rhythm Pharmaceuticals, Inc.'s industry peers?

60 issuers in our coverage, RYTM included, share the SEC industry code Pharmaceutical Preparations. The largest are: Eli Lilly & Co (LLY), Johnson & Johnson (JNJ), Abbvie Inc. (ABBV), Merck & Co., Inc. (MRK), Novartis Ag (NVS), Astrazeneca Plc (AZN).

This analysis is generated automatically using our proprietary AI systems and should not be considered personalized investment advice. Past performance does not guarantee future results. Always conduct your own research and consider consulting a financial advisor before making investment decisions.