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Model output · Signal date 2026-10-16

Opko Health, Inc. (OPK) Stock Forecast Oct. 16, 2026

Analysis updated on Oct. 16, 2026 (UTC) · Total · absolute moveSwitch to Alpha · Nasdaq

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Rating · 90D ▲ Bullish Exact rating locked
90-day forecast Sign up free to reveal
30-day forecast Total
Rank in coverage Top 35% of 5184 stocks scored
Rank correlation · 90D 39.0% Spearman, 357 dates
Market Cap $1.14B small-cap · #60 of 60 peers
Summary

Opko Health, Inc. (OPK) stock forecast summary

Our AI ranks Opko Health, Inc. outside the neutral middle of its coverage (a directional signal). Create a free account and follow it to see the exact price target.

Opko Health, Inc. is a small-cap company with a market capitalization of $1.14B. It ranks number 60 by market capitalization among the 60 Pharmaceutical Preparations issuers in our coverage with a current forecast. Its P/B Ratio of 0.87x is the lowest of the 42 peers that report one.

For OPK, the Spearman rank correlation between our 90-day forecasts and the returns that followed is 39.0%, measured on 357 forecast dates between 2022-07-29 and 2026-07-17 on this stock's own recent history. A rank correlation runs from -100% to +100%: it measures whether higher forecasts were followed by higher returns, and a value near zero or below means the model has shown little skill on this stock. On the 30-day forecasts the same correlation is 19.0%, measured on 400 forecast dates between 2022-07-29 and 2026-09-16. Across our coverage, the out-of-sample test on 4495 stocks from 2025-01-06 to 2026-07-07 produced a positive net return in 82.5% of rebalance periods (factor-neutral book, net of estimated costs). Full backtest report

Expected absolute price move over the horizon, market included. This is the number a price target is built from. Ratings: strong buy ≥ +5.1%, buy ≥ +3.4%, sell < +1.8%, strong sell < +0.8% (top 15%, next 20%, middle 30%, next 20%, bottom 15% of the 2026-10-16 signals)

A free account shows the exact forecast, rating and rank of 3 tickers you follow, OPK included.

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Price

OPK price chart and AI forecast

OPK
Cross-section · 2026-10-16

How OPK ranks among 5184 stocks

90D Total forecasts of every company scored, cut into five relative ratings at the 15th, 35th, 65th and 85th percentiles (dashed lines).

Fundamentals · 2026-06-30

Opko Health, Inc. (OPK) fundamentals

Trailing twelve months. The industry median and the rank (1 = highest) are taken over the Pharmaceutical Preparations peers listed below that report each metric.

Valuation & Market

MetricOPKIndustry medianRank
Market Cap $1.14B $11.72B 60/60
P/B Ratio 0.87x 7.27x 42/42
EPS $-0.12 – –
Book Value/Share $1.75 – –
Revenue/Share $0.97 – –
FCF/Share $-0.18 – –

Profitability & Margins

MetricOPKIndustry medianRank
Gross Margin 51.9% 81.9% 33/36
Operating Margin -8.0% 12.4% 27/39
EBT Margin -25.3% 12.5% 36/46
Tax Rate 4.5% – –

Financial Health

MetricOPKIndustry medianRank
Current Ratio 3.35x 3.08x 26/59
Quick Ratio 2.93x 1.51x 14/44
D/E Ratio 0.53x 1.23x 32/48
Interest Coverage -1.0x 1.1x 24/36
Working Capital $351M $863M 45/59

Cash Flow

MetricOPKIndustry medianRank
Operating Cash Flow -$123M $166M 45/59
Free Cash Flow -$134M $148M 38/50
Capital Spending -$11M -$55M 20/50
FCF/Sales -18.5% 16.8% 36/42
CapEx/Sales 1.5% 2.6% 30/42

Operational Efficiency

MetricOPKIndustry medianRank
Receivables Turnover 8.8x 5.2x 8/38
Inventory Turnover 5.6x 1.9x 4/36
Fixed Assets Turnover 10.1x 7.6x 18/41
Days Sales Outstanding 41 days 69 days 31/38
Days Inventory 65 days 194 days 33/36
Payables Period 52 days 150 days 23/26
Cash Conversion Cycle 54 days 193 days 17/24

Income Statement

MetricOPKIndustry medianRank
Total Revenue $724M $2.83B 36/46
Operating Income -$48M $93M 31/51
R&D Expense $125M $527M 53/58
SG&A Expense $206M $1.32B 41/41
Cost of Goods Sold $348M $1.76B 24/37

Dividend & Shareholder Information

MetricOPKIndustry medianRank
Shares Outstanding 746M – –

Balance Sheet Highlights (USD millions)

Total Current Assets$500M25.1% of assets
Cash & Short-term Investments$301M15.1% of assets
Accounts Receivable$82M4.1% of assets
Inventory$62M3.1% of assets
Total Liabilities$690M34.6% of assets
Short-term Debt$99M5.0% of assets
Quarterly Financial Reports

OPK quarterly financials and insider trading

Industry Peers · Pharmaceutical Preparations

Opko Health, Inc. (OPK) industry peers

Companies classified under the same SEC industry code as Opko Health, Inc. (Pharmaceutical Preparations): 60 common-stock issuers with a forecast this week, one row per issuer, largest first. This is a classification match, not a curated list of competitors.

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Company 90-Day AI Forecast (Total) Market Cap P/E Ratio P/B Ratio
OPK Opko Health, Inc. ▲ $1.14B – 0.9x
LLY Eli Lilly & Co ▼ $1.18T 42.2x 120.4x
JNJ Johnson & Johnson ▼ $615.87B 29.7x 7.3x
ABBV Abbvie Inc. ▼ $504.37B 73.8x –
MRK Merck & Co., Inc. ▶ $360.08B 116.8x 8.6x
NVS Novartis Ag ▼ $287.41B 9.0x –
AZN Astrazeneca Plc ▼ $256.39B 11.9x –
ABT Abbott Laboratories ▼ $182.39B 29.4x 3.5x
NVO Novo Nordisk A S ▼ $172.56B 2.9x –
PFE Pfizer Inc ▼ $168.60B 36.5x 2.0x
VRTX Vertex Pharmaceuticals Inc / Ma ▶ $126.66B 29.1x 6.3x
BMY Bristol Myers Squibb Co ▼ $122.05B 13.1x 5.5x
GSK Gsk Plc ▼ $100.46B 5.5x –
SNY Sanofi ▼ $100.12B – –
REGN Regeneron Pharmaceuticals, Inc. ▼ $81.76B 19.6x 2.6x
TAK Takeda Pharmaceutical Co Ltd ▼ $61.45B 5.9x –
TEVA Teva Pharmaceutical Industries Ltd ▼ $48.36B 86.5x 6.2x
ONC Beone Medicines Ltd. ▲ $41.96B 1272.7x 8.1x
ZTS Zoetis Inc. ▼ $32.80B 13.1x 10.4x
ALNY Alnylam Pharmaceuticals, Inc. ▶ $31.02B 58.3x 22.9x
RPRX Royalty Pharma Plc ▼ $26.88B 34.8x 3.9x
ROIV Roivant Sciences Ltd. ▲ $24.22B – 5.7x
GMAB Genmab A/S ▶ $23.80B 1.5x –
UTHR United Therapeutics Corp ▼ $22.87B 19.1x 3.6x
VTRS Viatris Inc ▼ $21.43B – –
INSM Insmed Inc ▶ $21.02B – 27.8x
ASND Ascendis Pharma A/S ▶ $14.85B – –
JAZZ Jazz Pharmaceuticals Plc ▼ $13.65B 14.4x 2.8x
BBIO Bridgebio Pharma, Inc. ▶ $12.98B – –
CORT Corcept Therapeutics Inc ▲ $11.91B 123.8x 16.9x
ELAN Elanco Animal Health Inc ▶ $11.77B – 1.8x
SMMT Summit Therapeutics Inc. ▲ $11.67B – 18.5x
RDY Dr Reddys Laboratories Ltd ▼ $10.91B 14.4x –
BMRN Biomarin Pharmaceutical Inc ▶ $10.58B 68.4x 1.7x
MDGL Madrigal Pharmaceuticals, Inc. ▼ $10.39B – 19.8x
CYTK Cytokinetics Inc ▲ $8.61B – –
TGTX Tg Therapeutics, Inc. ▶ $8.56B 20.4x 14.2x
PTGX Protagonist Therapeutics, Inc ▶ $8.33B 163.0x 9.9x
AXSM Axsome Therapeutics, Inc. ▲ $8.23B – 98.8x
ARWR Arrowhead Pharmaceuticals, Inc. ▲ $7.90B – 17.0x
ABVX Abivax S.A. ▼ $7.74B – –
IONS Ionis Pharmaceuticals Inc ▲ $7.14B – 16.2x
SYRE Spyre Therapeutics, Inc. ▲ $7.05B – 6.4x
ALKS Alkermes Plc. ▲ $6.92B 45.3x 3.8x
PRAX Praxis Precision Medicines, Inc. ▲ $6.75B – 5.0x
KNSA Kiniksa Pharmaceuticals International, Plc ▼ $6.13B 86.4x 10.1x
AMRX Amneal Pharmaceuticals, Inc. ▶ $6.13B 58.1x –
RYTM Rhythm Pharmaceuticals, Inc. ▲ $5.93B – 57.6x
LGND Ligand Pharmaceuticals Inc ▼ $5.89B 28.6x 6.1x
BLTE Belite Bio, Inc ▲ $5.62B – 7.3x
MIRM Mirum Pharmaceuticals, Inc. ▲ $5.20B – –
COGT Cogent Biosciences, Inc. ▲ $5.12B – 9.6x
PTCT Ptc Therapeutics, Inc. ▶ $4.94B – –
ORKA Oruka Therapeutics, Inc. ▲ $4.76B – 4.3x
ERAS Erasca, Inc. ▲ $4.68B – 12.9x
MANE Veradermics, Inc ▲ $4.55B – 5.6x
TVTX Travere Therapeutics, Inc. ▲ $4.44B – 181.0x
EWTX Edgewise Therapeutics, Inc. ▲ $4.04B – 9.0x
DNTH Dianthus Therapeutics, Inc. /De/ ▲ $4.03B – 3.4x
INDV Indivior Pharmaceuticals, Inc. ▼ $3.83B 13.1x –

Where OPK sits on the market map

Life Sciences · Pharmaceutical Preparations
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News

Opko Health, Inc. (OPK) stock news

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FAQ

Opko Health, Inc. (OPK) stock forecast FAQ

What is the Opko Health, Inc. (OPK) stock forecast?

Our AI ranks Opko Health, Inc. outside the neutral middle of its coverage (a directional signal). Create a free account and follow it to see the exact price target.

How accurate are Opko Health, Inc. stock predictions?

For OPK, the Spearman rank correlation between our 90-day forecasts and the returns that followed is 39.0%, measured on 357 forecast dates between 2022-07-29 and 2026-07-17 on this stock's own recent history. A rank correlation runs from -100% to +100%: it measures whether higher forecasts were followed by higher returns, and a value near zero or below means the model has shown little skill on this stock. On the 30-day forecasts the same correlation is 19.0%, measured on 400 forecast dates between 2022-07-29 and 2026-09-16. Across our coverage, the out-of-sample test on 4495 stocks from 2025-01-06 to 2026-07-07 produced a positive net return in 82.5% of rebalance periods (factor-neutral book, net of estimated costs). Full backtest report

How often are Opko Health, Inc. forecasts updated?

Opko Health, Inc. forecasts are refreshed on trading days as the daily model run completes. The forecast on this page was produced on Oct. 16, 2026.

Which companies are Opko Health, Inc.'s industry peers?

60 issuers in our coverage, OPK included, share the SEC industry code Pharmaceutical Preparations. The largest are: Eli Lilly & Co (LLY), Johnson & Johnson (JNJ), Abbvie Inc. (ABBV), Merck & Co., Inc. (MRK), Novartis Ag (NVS), Astrazeneca Plc (AZN).

This analysis is generated automatically using our proprietary AI systems and should not be considered personalized investment advice. Past performance does not guarantee future results. Always conduct your own research and consider consulting a financial advisor before making investment decisions.