VRTX - Vertex Pharmaceuticals Incorporated
Vertex Pharmaceuticals Incorporated is currently listed on NASDAQ under VRTX. One share of VRTX stock can currently be purchased for approximately $507.00. Is Vertex Pharmaceuticals Incorporated (VRTX ...
Model output · Signal date 2026-10-16
Vertex Pharmaceuticals Inc / Ma (VRTX) Stock Forecast Oct. 16, 2026
Analysis updated on Oct. 16, 2026 (UTC) · Alpha · vs marketSwitch to Total · Nasdaq
Rating · 90D
Alpha
90-day forecast
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30-day forecast
Alpha
Rank in coverage
Middle 30%
of 5184 stocks scored
Rank correlation · 90D
14.0%
Spearman, 357 dates
Market Cap
$126.66B
large-cap · #10 of 60 peers
Summary
Vertex Pharmaceuticals Inc / Ma (VRTX) stock forecast summary
On Oct. 16, 2026, VRTX is rated Neutral: its 90-day Alpha forecast sits in the middle 30% of the 5184 stocks scored that day.
Vertex Pharmaceuticals Inc / Ma is a large-cap company with a market capitalization of $126.66B. It ranks number 10 by market capitalization among the 60 Pharmaceutical Preparations issuers in our coverage with a current forecast.
For VRTX, the Spearman rank correlation between our 90-day forecasts and the returns that followed is 14.0%, measured on 357 forecast dates between 2022-07-29 and 2026-07-17 on this stock's own recent history. A rank correlation runs from -100% to +100%: it measures whether higher forecasts were followed by higher returns, and a value near zero or below means the model has shown little skill on this stock. On the 30-day forecasts the same correlation is -5.0%, measured on 400 forecast dates between 2022-07-29 and 2026-09-16. Across our coverage, the out-of-sample test on 4495 stocks from 2025-01-06 to 2026-07-07 produced a positive net return in 82.5% of rebalance periods (factor-neutral book, net of estimated costs). Full backtest report
Expected return relative to the market over the horizon: a positive alpha means the model expects the stock to beat the market, whatever the market does. Ratings: strong buy ≥ +1.8%, buy ≥ +0.2%, sell < -0.9%, strong sell < -1.2% (top 15%, next 20%, middle 30%, next 20%, bottom 15% of the 2026-10-16 signals)
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VRTX price chart and AI forecast
Cross-section · 2026-10-16
How VRTX ranks among 5184 stocks
90D Alpha forecasts of every company scored, cut into five relative ratings at the 15th, 35th, 65th and 85th percentiles (dashed lines).
Fundamentals · 2026-06-30
Vertex Pharmaceuticals Inc / Ma (VRTX) fundamentals
Trailing twelve months. The industry median and the rank (1 = highest) are taken over the Pharmaceutical Preparations peers listed below that report each metric.
Valuation & Market
| Metric | VRTX | Rank |
|---|---|---|
| Market Cap | $126.66B | 10/60 |
| P/E Ratio | 29.11x | 17/32 |
| P/B Ratio | 6.26x | 24/42 |
| EPS | $17.17 | – |
| Book Value/Share | $79.89 | – |
| Revenue/Share | $49.66 | – |
| FCF/Share | $14.98 | – |
Profitability & Margins
| Metric | VRTX | Rank |
|---|---|---|
| ROE | 21.8% | 10/38 |
| ROA | 16.1% | 9/43 |
| ROIC | 20.3% | 8/46 |
| Gross Margin | 86.0% | 12/35 |
| Operating Margin | 38.0% | 6/39 |
| Net Margin | 35.0% | 5/35 |
| EBT Margin | 41.9% | 8/46 |
| Tax Rate | 16.5% | – |
Financial Health
| Metric | VRTX | Rank |
|---|---|---|
| Current Ratio | 3.19x | 29/59 |
| Quick Ratio | 2.74x | 16/43 |
| D/E Ratio | 0.35x | 33/48 |
| Financial Leverage | 1.35x | 32/48 |
| Interest Coverage | 402.2x | 1/36 |
| Working Capital | $8.61B | 6/59 |
Cash Flow
| Metric | VRTX | Rank |
|---|---|---|
| Operating Cash Flow | $4.29B | 15/59 |
| Free Cash Flow | $3.80B | 12/50 |
| Capital Spending | -$497M | 35/50 |
| OCF Growth YoY | 11.6% | 16/33 |
| FCF Growth YoY | 8.5% | 11/31 |
| FCF/Sales | 30.2% | 7/42 |
| CapEx/Sales | 4.0% | 17/42 |
Operational Efficiency
| Metric | VRTX | Rank |
|---|---|---|
| Asset Turnover | 0.46x | 23/40 |
| Receivables Turnover | 5.9x | 13/37 |
| Inventory Turnover | 1.0x | 26/35 |
| Fixed Assets Turnover | 7.6x | 22/41 |
| Days Sales Outstanding | 62 days | 25/37 |
| Days Inventory | 365 days | 10/35 |
| Payables Period | 89 days | 19/25 |
| Cash Conversion Cycle | 338 days | 6/23 |
Income Statement
| Metric | VRTX | Rank |
|---|---|---|
| Total Revenue | $12.59B | 14/46 |
| Operating Income | $4.78B | 9/51 |
| Net Income | $4.41B | 10/46 |
| R&D Expense | $3.91B | 13/58 |
| SG&A Expense | $2.01B | 17/40 |
| Cost of Goods Sold | $1.76B | 19/36 |
Dividend & Shareholder Information
| Metric | VRTX | Rank |
|---|---|---|
| Shares Outstanding | 253M | – |
| Net Income Growth | 21.1% | 7/18 |
| EPS Growth | 21.7% | 9/24 |
Balance Sheet Highlights (USD millions)
| Total Current Assets | $12.54B | 45.7% of assets |
| Cash & Short-term Investments | $6.14B | 22.4% of assets |
| Accounts Receivable | $2.13B | 7.8% of assets |
| Inventory | $1.77B | 6.4% of assets |
| Total Liabilities | $7.18B | 26.2% of assets |
| Short-term Debt | $3.51B | 12.8% of assets |
Quarterly Financial Reports
VRTX quarterly financials and insider trading
Industry Peers · Pharmaceutical Preparations
Vertex Pharmaceuticals Inc / Ma (VRTX) industry peers
Companies classified under the same SEC industry code as Vertex Pharmaceuticals Inc / Ma (Pharmaceutical Preparations): 60 common-stock issuers with a forecast this week, one row per issuer, largest first. This is a classification match, not a curated list of competitors.
Reveal all forecasts · See exact % predictions for all competitors
Sign up free| Company | 90-Day AI Forecast (Alpha) | Market Cap |
|---|---|---|
| VRTX Vertex Pharmaceuticals Inc / Ma | ▶ | $126.66B |
| LLY Eli Lilly & Co | ▶ | $1.18T |
| JNJ Johnson & Johnson | ▼ | $615.87B |
| ABBV Abbvie Inc. | ▶ | $504.37B |
| MRK Merck & Co., Inc. | ▲ | $360.08B |
| NVS Novartis Ag | ▼ | $287.41B |
| AZN Astrazeneca Plc | ▼ | $256.39B |
| ABT Abbott Laboratories | ▼ | $182.39B |
| NVO Novo Nordisk A S | ▼ | $172.56B |
| PFE Pfizer Inc | ▶ | $168.60B |
| BMY Bristol Myers Squibb Co | ▶ | $122.05B |
| GSK Gsk Plc | ▼ | $100.46B |
| SNY Sanofi | ▼ | $100.12B |
| REGN Regeneron Pharmaceuticals, Inc. | ▶ | $81.76B |
| TAK Takeda Pharmaceutical Co Ltd | ▼ | $61.45B |
| TEVA Teva Pharmaceutical Industries Ltd | ▼ | $48.36B |
| ONC Beone Medicines Ltd. | ▲ | $41.96B |
| ZTS Zoetis Inc. | ▼ | $32.80B |
| ALNY Alnylam Pharmaceuticals, Inc. | ▶ | $31.02B |
| RPRX Royalty Pharma Plc | ▶ | $26.88B |
| ROIV Roivant Sciences Ltd. | ▲ | $24.22B |
| GMAB Genmab A/S | ▲ | $23.80B |
| UTHR United Therapeutics Corp | ▶ | $22.87B |
| VTRS Viatris Inc | ▼ | $21.43B |
| INSM Insmed Inc | ▶ | $21.02B |
| ASND Ascendis Pharma A/S | ▲ | $14.85B |
| JAZZ Jazz Pharmaceuticals Plc | ▼ | $13.65B |
| BBIO Bridgebio Pharma, Inc. | ▶ | $12.98B |
| CORT Corcept Therapeutics Inc | ▲ | $11.91B |
| ELAN Elanco Animal Health Inc | ▼ | $11.77B |
| SMMT Summit Therapeutics Inc. | ▶ | $11.67B |
| RDY Dr Reddys Laboratories Ltd | ▼ | $10.91B |
| BMRN Biomarin Pharmaceutical Inc | ▶ | $10.58B |
| MDGL Madrigal Pharmaceuticals, Inc. | ▶ | $10.39B |
| CYTK Cytokinetics Inc | ▲ | $8.61B |
| TGTX Tg Therapeutics, Inc. | ▲ | $8.56B |
| PTGX Protagonist Therapeutics, Inc | ▶ | $8.33B |
| AXSM Axsome Therapeutics, Inc. | ▲ | $8.23B |
| ARWR Arrowhead Pharmaceuticals, Inc. | ▲ | $7.90B |
| ABVX Abivax S.A. | ▼ | $7.74B |
| IONS Ionis Pharmaceuticals Inc | ▲ | $7.14B |
| SYRE Spyre Therapeutics, Inc. | ▲ | $7.05B |
| ALKS Alkermes Plc. | ▲ | $6.92B |
| PRAX Praxis Precision Medicines, Inc. | ▲ | $6.75B |
| KNSA Kiniksa Pharmaceuticals International, Plc | ▶ | $6.13B |
| AMRX Amneal Pharmaceuticals, Inc. | ▲ | $6.13B |
| RYTM Rhythm Pharmaceuticals, Inc. | ▲ | $5.93B |
| LGND Ligand Pharmaceuticals Inc | ▶ | $5.89B |
| BLTE Belite Bio, Inc | ▲ | $5.62B |
| MIRM Mirum Pharmaceuticals, Inc. | ▲ | $5.20B |
| COGT Cogent Biosciences, Inc. | ▶ | $5.12B |
| PTCT Ptc Therapeutics, Inc. | ▲ | $4.94B |
| ORKA Oruka Therapeutics, Inc. | ▲ | $4.76B |
| ERAS Erasca, Inc. | ▲ | $4.68B |
| MANE Veradermics, Inc | ▲ | $4.55B |
| TVTX Travere Therapeutics, Inc. | ▲ | $4.44B |
| EWTX Edgewise Therapeutics, Inc. | ▲ | $4.04B |
| DNTH Dianthus Therapeutics, Inc. /De/ | ▲ | $4.03B |
| INDV Indivior Pharmaceuticals, Inc. | ▶ | $3.83B |
| TNGX Tango Therapeutics, Inc. | ▲ | $3.72B |
Where VRTX sits on the market map
Life Sciences · Pharmaceutical Preparations
News
Vertex Pharmaceuticals Inc / Ma (VRTX) stock news
Vertex Pharmaceuticals, Inc. (VRTX) CEO Reshma Kewalramani on Q2 2022 Results - Earnings Call Transcript
Vertex Pharmaceuticals, Inc. (VRTX) Q2 2022 Earnings Conference Call August 04, 2022, 16:30 ET Company Participants Charles Wagner - EVP & CFO Reshma ...
Vertex Pharmaceuticals Inc (VX1D.XD) Q3 FY2025 earnings call transcript
Vertex delivered strong Q3 2025 results with revenue up 11% YoY to $3.08B, driven by continued CF franchise growth and new product launches (Aliftrack, Jurnavix, Casgevy). Management raised full-year ...
FAQ
Vertex Pharmaceuticals Inc / Ma (VRTX) stock forecast FAQ
What is the Vertex Pharmaceuticals Inc / Ma (VRTX) stock forecast?
On Oct. 16, 2026, VRTX is rated Neutral: its 90-day Alpha forecast sits in the middle 30% of the 5184 stocks scored that day.
How accurate are Vertex Pharmaceuticals Inc / Ma stock predictions?
For VRTX, the Spearman rank correlation between our 90-day forecasts and the returns that followed is 14.0%, measured on 357 forecast dates between 2022-07-29 and 2026-07-17 on this stock's own recent history. A rank correlation runs from -100% to +100%: it measures whether higher forecasts were followed by higher returns, and a value near zero or below means the model has shown little skill on this stock. On the 30-day forecasts the same correlation is -5.0%, measured on 400 forecast dates between 2022-07-29 and 2026-09-16. Across our coverage, the out-of-sample test on 4495 stocks from 2025-01-06 to 2026-07-07 produced a positive net return in 82.5% of rebalance periods (factor-neutral book, net of estimated costs). Full backtest report
How often are Vertex Pharmaceuticals Inc / Ma forecasts updated?
Vertex Pharmaceuticals Inc / Ma forecasts are refreshed on trading days as the daily model run completes. The forecast on this page was produced on Oct. 16, 2026.
Which companies are Vertex Pharmaceuticals Inc / Ma's industry peers?
60 issuers in our coverage, VRTX included, share the SEC industry code Pharmaceutical Preparations. The largest are: Eli Lilly & Co (LLY), Johnson & Johnson (JNJ), Abbvie Inc. (ABBV), Merck & Co., Inc. (MRK), Novartis Ag (NVS), Astrazeneca Plc (AZN).
This analysis is generated automatically using our proprietary AI systems and should not be considered personalized investment advice. Past performance does not guarantee future results. Always conduct your own research and consider consulting a financial advisor before making investment decisions.