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Model output · Signal date 2026-11-06

Taysha Gene Therapies, Inc. (TSHA) Stock Forecast Nov. 6, 2026

Analysis updated on Nov. 6, 2026 (UTC) · Alpha · vs marketSwitch to Total · Nasdaq

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Rating · 90D Unlock rating and forecasts
90-day forecast Sign up free to reveal
30-day forecast Alpha
Rank in coverage of 5150 stocks scored
Rank correlation · 90D -27.0% Spearman, 357 dates
Market Cap $1.41B small-cap · #43 of 60 peers
Summary

Taysha Gene Therapies, Inc. (TSHA) stock forecast summary

Our AI scores Taysha Gene Therapies, Inc. every trading day against every stock it covers. Create a free account and follow it to see its rating and price target.

Taysha Gene Therapies, Inc. is a small-cap company with a market capitalization of $1.41B. It ranks number 43 by market capitalization among the 60 Biological Products, (No Diagnostic Substances) issuers in our coverage with a current forecast.

For TSHA, the Spearman rank correlation between our 90-day forecasts and the returns that followed is -27.0%, measured on 357 forecast dates between 2022-08-19 and 2026-08-07 on this stock's own recent history. A rank correlation runs from -100% to +100%: it measures whether higher forecasts were followed by higher returns, and a value near zero or below means the model has shown little skill on this stock. On the 30-day forecasts the same correlation is -3.0%, measured on 400 forecast dates between 2022-08-19 and 2026-10-07. Across our coverage, the out-of-sample test on 4629 stocks from 2025-01-06 to 2026-08-04 produced a positive net return in 92.9% of rebalance periods (factor-neutral book, net of estimated costs). Full backtest report

Expected return relative to the market over the horizon: a positive alpha means the model expects the stock to beat the market, whatever the market does. Ratings: strong buy ≥ +3.1%, buy ≥ +1.5%, sell < -0.5%, strong sell < -1.8% (top 15%, next 20%, middle 30%, next 20%, bottom 15% of the 2026-11-06 signals)

A free account shows the exact forecast, rating and rank of 3 tickers you follow, TSHA included.

Price

TSHA price chart and AI forecast

TSHA
Cross-section · 2026-11-06

How TSHA ranks among 5150 stocks

90D Alpha forecasts of every company scored, cut into five relative ratings at the 15th, 35th, 65th and 85th percentiles (dashed lines).

Fundamentals · 2026-06-30

Taysha Gene Therapies, Inc. (TSHA) fundamentals

Trailing twelve months. The industry median and the rank (1 = highest) are taken over the Biological Products, (No Diagnostic Substances) peers listed below that report each metric.

Valuation & Market

MetricTSHAIndustry medianRank
Market Cap $1.41B $2.69B 43/60
P/B Ratio 3.64x 5.01x 34/48
EPS $-0.38 – –
Book Value/Share $1.19 – –
Revenue/Share $0.02 – –
FCF/Share $-0.41 – –

Profitability & Margins

MetricTSHAIndustry medianRank
ROE -38.6% -30.7% 25/43
ROA -31.8% -21.5% 29/46
ROIC -34.5% -27.5% 30/52
Operating Margin -2792.3% -47.8% 35/40
Net Margin -2728.0% -31.7% 32/35
EBT Margin -2792.3% -47.7% 37/42
Tax Rate 0.0% – –

Financial Health

MetricTSHAIndustry medianRank
Current Ratio 17.76x 5.72x 4/59
D/E Ratio 0.21x 0.38x 36/51
Financial Leverage 1.21x 1.39x 35/50
Interest Coverage -32.8x -22.3x 20/37
Working Capital $435M $440M 30/58

Cash Flow

MetricTSHAIndustry medianRank
Operating Cash Flow -$132M -$141M 27/56
Free Cash Flow -$133M -$107M 26/49
Capital Spending -$380K -$6M 9/49
FCF/Sales -2417.0% -3.6% 30/32
CapEx/Sales 7.0% 3.0% 8/32

Operational Efficiency

MetricTSHAIndustry medianRank
Asset Turnover 0.01x 0.32x 32/37
Fixed Assets Turnover 2.3x 4.2x 26/38

Income Statement

MetricTSHAIndustry medianRank
Total Revenue $5M $389M 35/38
Operating Income -$153M -$157M 26/53
Net Income -$150M -$182M 22/46
R&D Expense $123M $201M 40/55

Dividend & Shareholder Information

MetricTSHAIndustry medianRank
Shares Outstanding 326M – –

Balance Sheet Highlights (USD millions)

Total Current Assets$461M98.0% of assets
Cash & Short-term Investments$455M96.7% of assets
Total Liabilities$83M17.7% of assets
Short-term Debt$17M3.6% of assets
Quarterly Financial Reports

TSHA quarterly financials and insider trading

Industry Peers · Biological Products, (No Diagnostic Substances)

Taysha Gene Therapies, Inc. (TSHA) industry peers

Companies classified under the same SEC industry code as Taysha Gene Therapies, Inc. (Biological Products, (No Diagnostic Substances)): 60 common-stock issuers with a forecast this week, one row per issuer, largest first. This is a classification match, not a curated list of competitors.

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Company 90-Day AI Forecast (Alpha) Market Cap P/E Ratio P/B Ratio
TSHA Taysha Gene Therapies, Inc. $1.41B – 3.6x
AMGN Amgen Inc $248.92B 26.7x 17.3x
GILD Gilead Sciences, Inc. $207.00B – 15.9x
MRNA Moderna, Inc. $101.48B – 14.8x
ARGX Argenx Se $57.38B 24.3x –
RVMD Revolution Medicines, Inc. $38.08B – 15.9x
BIIB Biogen Inc. $36.71B 107.1x 1.9x
BNTX Biontech Se $22.13B 2.3x –
EXEL Exelixis, Inc. $16.98B 25.0x 9.3x
NBIX Neurocrine Biosciences Inc $16.73B 24.1x 4.3x
HALO Halozyme Therapeutics, Inc. $13.96B 24.9x –
TECH Bio-Techne Corp $11.43B 66.2x 5.3x
KYMR Kymera Therapeutics, Inc. $11.25B – 7.0x
RGEN Repligen Corp $11.09B – 5.3x
QGEN Qiagen N.V. $10.92B 35.7x 2.9x
PCVX Vaxcyte, Inc. $9.51B – 3.8x
IBRX Immunitybio, Inc. $9.15B – –
KRYS Krystal Biotech, Inc. $8.92B 40.9x 6.2x
TWST Twist Bioscience Corp $7.57B – 17.0x
CGON Cg Oncology, Inc. $6.74B – 6.8x
IMVT Immunovant, Inc. $6.31B – 8.6x
KOD Kodiak Sciences Inc. $6.24B – 102.2x
SRRK Scholar Rock Holding Corp $5.54B – 21.8x
CRSP Crispr Therapeutics Ag $4.84B – 2.9x
ADPT Adaptive Biotechnologies Corp $4.47B – 25.3x
RLAY Relay Therapeutics, Inc. $4.08B – 5.0x
IOVA Iovance Biotherapeutics, Inc. $3.51B – 4.3x
TARS Tarsus Pharmaceuticals, Inc. $3.33B – 32.0x
DNLI Denali Therapeutics Inc. $3.21B – 3.5x
ADMA Adma Biologics, Inc. $2.85B 19.0x 6.5x
BEAM Beam Therapeutics Inc. $2.73B 377.3x 2.9x
VCEL Vericel Corp $2.65B 105.7x 6.9x
COAG Hemab Therapeutics Holdings, Inc. $2.29B – 5.0x
RXRX Recursion Pharmaceuticals, Inc. $2.18B – 2.4x
LIFE Atyr Pharma Inc $2.14B – 62.9x
REPL Replimune Group, Inc. $2.05B – 10.0x
BCRX Biocryst Pharmaceuticals Inc $1.97B – –
MAZE Maze Therapeutics, Inc. $1.90B – 4.2x
VIR Vir Biotechnology, Inc. $1.86B – 2.1x
MESO Mesoblast Ltd $1.83B – –
NVAX Novavax Inc $1.78B 119.8x –
ALVO Alvotech $1.73B – –
IMCR Immunocore Holdings Plc $1.60B – 3.8x
VOR Vor Biopharma Inc. $1.15B – –
ODTX Odyssey Therapeutics, Inc. $924M – 2.5x
GLUE Monte Rosa Therapeutics, Inc. $902M – 1.8x
PRME Prime Medicine, Inc. $843M – 21.2x
IMTX Immatics N.V. $829M – –
MGTX Meiragtx Holdings Plc $817M 11.1x 3.8x
DNA Ginkgo Bioworks Holdings, Inc. $760M – 1.8x
CGEM Cullinan Therapeutics, Inc. $728M – 2.3x
SANA Sana Biotechnology, Inc. $709M – 3.9x
SLDB Solid Biosciences Inc. $707M – 2.1x
AURA Aura Biosciences, Inc. $680M – 2.2x
FDMT 4d Molecular Therapeutics, Inc. $676M – 1.7x
CADL Candel Therapeutics, Inc. $670M – 5.3x
DBVT Dbv Technologies S.A. $616M – 3.7x
SRZN Surrozen, Inc./De $542M – –
ENTX Entera Bio Ltd. $518M 9.1x 71.3x
SLBT Sl Science Holding Ltd $513M – –

Where TSHA sits on the market map

Life Sciences · Biological Products, (No Diagnostic Substances)
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News

Taysha Gene Therapies, Inc. (TSHA) stock news

Taysha Gene Therapies Inc is a clinical-stage biotechnology company, which is focused on advancing adeno-associated virus (AAV)-based gene therapies for severe monogenic diseases of the central ...

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FAQ

Taysha Gene Therapies, Inc. (TSHA) stock forecast FAQ

What is the Taysha Gene Therapies, Inc. (TSHA) stock forecast?

Our AI scores Taysha Gene Therapies, Inc. every trading day against every stock it covers. Create a free account and follow it to see its rating and price target.

How accurate are Taysha Gene Therapies, Inc. stock predictions?

For TSHA, the Spearman rank correlation between our 90-day forecasts and the returns that followed is -27.0%, measured on 357 forecast dates between 2022-08-19 and 2026-08-07 on this stock's own recent history. A rank correlation runs from -100% to +100%: it measures whether higher forecasts were followed by higher returns, and a value near zero or below means the model has shown little skill on this stock. On the 30-day forecasts the same correlation is -3.0%, measured on 400 forecast dates between 2022-08-19 and 2026-10-07. Across our coverage, the out-of-sample test on 4629 stocks from 2025-01-06 to 2026-08-04 produced a positive net return in 92.9% of rebalance periods (factor-neutral book, net of estimated costs). Full backtest report

How often are Taysha Gene Therapies, Inc. forecasts updated?

Taysha Gene Therapies, Inc. forecasts are refreshed on trading days as the daily model run completes. The forecast on this page was produced on Nov. 6, 2026.

Which companies are Taysha Gene Therapies, Inc.'s industry peers?

60 issuers in our coverage, TSHA included, share the SEC industry code Biological Products, (No Diagnostic Substances). The largest are: Amgen Inc (AMGN), Gilead Sciences, Inc. (GILD), Moderna, Inc. (MRNA), Argenx Se (ARGX), Revolution Medicines, Inc. (RVMD), Biogen Inc. (BIIB).

This analysis is generated automatically using our proprietary AI systems and should not be considered personalized investment advice. Past performance does not guarantee future results. Always conduct your own research and consider consulting a financial advisor before making investment decisions.